Blar i forfatter "Gossmann, Toni Ingolf"

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    • Evidence for Strong Fixation Bias at 4-fold Degenerate Sites Across Genes in the Great Tit Genome 

      Gossmann, Toni Ingolf; Bockwoldt, Mathias; Diringer, Lilith; Schwarz, Friedrich; Schumann, Vic-Fabienne (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-11-29)
      It is well established that GC content varies across the genome in many species and that GC biased gene conversion, one form of meiotic recombination, is likely to contribute to this heterogeneity. Bird genomes provide an extraordinary system to study the impact of GC biased gene conversion owed to their specific genomic features. They are characterized by a high karyotype conservation with ...

    • Human long intrinsically disordered protein regions are frequent targets of positive selection 

      Afanasyeva, Arina; Bockwoldt, Mathias; Cooney, Christopher; Heiland, Ines; Gossmann, Toni Ingolf (Journal article; Tidsskriftartikkel; Peer reviewed, 2018-06-01)
      Intrinsically disordered regions occur frequently in proteins and are characterized by a lack of a well-defined three-dimensional structure. Although these regions do not show a higher order of structural organization, they are known to be functionally important. Disordered regions are rapidly evolving, largely attributed to relaxed purifying selection and an increased role of genetic drift. It has ...